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Polyubiquitination Events Mediate Polymethylmethacrylate (PMMA) Particle Activation of NF-κB Pathway

The pathologic response to implant wear-debris constitutes a major component of inflammatory osteolysis and remains under intense investigation. Polymethylmethacrylate (PMMA) particles, which are released during implant wear and loosening, constitute a major culprit by virtue of inducing inflammator...

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Bibliografiska uppgifter
Huvudupphovsmän: Yamanaka, Yasuhiro, Karuppaiah, Kannan, Abu-Amer, Yousef
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Biochemistry and Molecular Biology 2011
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3129154/
https://ncbi.nlm.nih.gov/pubmed/21566132
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.223669
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