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Iron Regulatory Protein 2 Turnover through a Nonproteasomal Pathway
Iron regulatory protein 2 (IRP2) controls the synthesis of many proteins involved in iron metabolism, and the level of IRP2 itself is regulated by varying the rate of its degradation. The proteasome is known to mediate degradation, with specificity conferred by an iron-sensing E3 ligase. Most studie...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3129150/ https://ncbi.nlm.nih.gov/pubmed/21558272 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.216788 |
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