Degradation of p53 by adenovirus E4orf6 and E1B55K proteins occurs via a novel mechanism involving a Cullin-containing complex
Although MDM2 plays a major role in regulating the stability of the p53 tumor suppressor protein, other poorly understood MDM2-independent pathways also exist. Human adenoviruses have evolved strategies to regulate p53 function and stability to permit efficient viral replication. One mechanism invol...
Kaydedildi:
| Yayımlandı: | Genes Dev |
|---|---|
| Asıl Yazarlar: | , , , , , , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Cold Spring Harbor Laboratory Press
2001
|
| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC312842/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11731475/ https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.926401 |
| Etiketler: |
Etiket eklenmemiş, İlk siz ekleyin!
|