Dmp1 is haplo-insufficient for tumor suppression and modifies the frequencies of Arf and p53 mutations in Myc-induced lymphomas

Loss of Dmp1, an Arf transcriptional activator, leads to spontaneous tumorigenesis in mice, causing death from various forms of cancer by two years of age. Retention and expression of the wild-type Dmp1 allele in tumors arising in Dmp1(+/−) mice demonstrate that Dmp1 can be haplo-insufficient for tu...

Deskribapen osoa

Xehetasun bibliografikoak

Argitaratua izan da:	Genes Dev
Egile Nagusiak:	Inoue, Kazushi, Zindy, Frederique, Randle, David H., Rehg, Jerold E., Sherr, Charles J.
Formatua:	Artigo
Hizkuntza:	Inglês
Argitaratua:	Cold Spring Harbor Laboratory Press 2001
Gaiak:	Research Communication
Sarrera elektronikoa:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC312824/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11711428/ https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.929901
Etiketak:	Etiketa erantsi Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!