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Human neutrophil FcγRIIA regulation by C5aR promotes inflammatory arthritis in mice

OBJECTIVE: Rheumatoid arthritis culminates in joint destruction that in mouse models of disease, is supported by innate immune molecules including FcγRs and complement. However, the results may not predict outcomes in humans given the structural differences between murine and human activating FcγRs...

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Autores principales: Tsuboi, Naotake, Ernandez, Thomas, Li, Xun, Nishi, Hiroshi, Cullere, Xavier, Mekala, Divya, Hazen, Melissa, Köhl, Jörg, Lee, David M., Mayadas, Tanya N.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2011
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3128197/
https://ncbi.nlm.nih.gov/pubmed/21280001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.30141
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