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Burn and smoke injury activates poly(ADP-ribose)polymerase in circulating leukocytes

The nuclear enzyme poly(ADP-ribose)polymerase (PARP) plays a significant role in the pathogenesis of various forms of critical illness. DNA strand breaks induced by oxidative and nitrative stress trigger the activation of PARP, and PARP, in turn, mediates cell death and promotes pro-inflammatory res...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Bartha, Eva, Asmussen, Sven, Olah, Gabor, Rehberg, Sebastian W., Yamamoto, Yusuke, Traber, Daniel L., Szabo, Csaba
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2011
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3128177/
https://ncbi.nlm.nih.gov/pubmed/21330947
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/SHK.0b013e318212988c
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