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Dynamic expression and essential functions of Hes7 in somite segmentation
The basic helix–loop–helix (bHLH) gene Hes7, a putative Notch effector, encodes a transcriptional repressor. Here, we found that Hes7 expression oscillates in 2-h cycles in the presomitic mesoderm (PSM). In Hes7-null mice, somites are not properly segmented and their anterior–posterior polarity is d...
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| Hoofdauteurs: | , , , , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Cold Spring Harbor Laboratory Press
2001
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC312810/ https://ncbi.nlm.nih.gov/pubmed/11641270 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.930601 |
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