Dynamic expression and essential functions of Hes7 in somite segmentation

The basic helix–loop–helix (bHLH) gene Hes7, a putative Notch effector, encodes a transcriptional repressor. Here, we found that Hes7 expression oscillates in 2-h cycles in the presomitic mesoderm (PSM). In Hes7-null mice, somites are not properly segmented and their anterior–posterior polarity is d...

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Dades bibliogràfiques

Publicat a:	Genes Dev
Autors principals:	Bessho, Yasumasa, Sakata, Ryoichi, Komatsu, Suguru, Shiota, Kohei, Yamada, Shuichi, Kageyama, Ryoichiro
Format:	Artigo
Idioma:	Inglês
Publicat:	Cold Spring Harbor Laboratory Press 2001
Matèries:	Research Communication
Accés en línia:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC312810/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11641270/ https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.930601
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