Broad Antiviral Activity of Carbohydrate-Binding Agents against the Four Serotypes of Dengue Virus in Monocyte-Derived Dendritic Cells

BACKGROUND: Dendritic cells (DC), present in the skin, are the first target cells of dengue virus (DENV). Dendritic cell-specific intercellular adhesion molecule 3-grabbing non-integrin (DC-SIGN) is present on DC and recognizes N-glycosylation sites on the E-glycoprotein of DENV. Thus, the DC-SIGN/E...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Alen, Marijke M. F., De Burghgraeve, Tine, Kaptein, Suzanne J. F., Balzarini, Jan, Neyts, Johan, Schols, Dominique
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2011
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3128091/
https://ncbi.nlm.nih.gov/pubmed/21738755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0021658
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