Human stem cell-derived hepatocyte-like cells support Zika virus replication and provide a relevant model to assess the efficacy of potential antivirals

Zika virus (ZIKV) infection during pregnancy has been extensively linked to microcephaly in newborns. High levels of ZIKV RNA were, however, also detected in mice and non-human primates in organs other than the brain, such as the liver. As ZIKV is a flavivirus closely related to the dengue and yello...

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Udgivet i:PLoS One
Main Authors: Tricot, Tine, Helsen, Nicky, Kaptein, Suzanne J. F., Neyts, Johan, Verfaillie, Catherine M.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2018
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6300258/
https://ncbi.nlm.nih.gov/pubmed/30566505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0209097
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