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Human stem cell-derived hepatocyte-like cells support Zika virus replication and provide a relevant model to assess the efficacy of potential antivirals

Zika virus (ZIKV) infection during pregnancy has been extensively linked to microcephaly in newborns. High levels of ZIKV RNA were, however, also detected in mice and non-human primates in organs other than the brain, such as the liver. As ZIKV is a flavivirus closely related to the dengue and yello...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Tricot, Tine, Helsen, Nicky, Kaptein, Suzanne J. F., Neyts, Johan, Verfaillie, Catherine M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6300258/
https://ncbi.nlm.nih.gov/pubmed/30566505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0209097
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