Human stem cell-derived hepatocyte-like cells support Zika virus replication and provide a relevant model to assess the efficacy of potential antivirals

Zika virus (ZIKV) infection during pregnancy has been extensively linked to microcephaly in newborns. High levels of ZIKV RNA were, however, also detected in mice and non-human primates in organs other than the brain, such as the liver. As ZIKV is a flavivirus closely related to the dengue and yello...

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Dades bibliogràfiques
Publicat a:PLoS One
Autors principals: Tricot, Tine, Helsen, Nicky, Kaptein, Suzanne J. F., Neyts, Johan, Verfaillie, Catherine M.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2018
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6300258/
https://ncbi.nlm.nih.gov/pubmed/30566505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0209097
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