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Antisense RNA polymerase II divergent transcripts are P-TEFb dependent and substrates for the RNA exosome

Divergent transcription occurs at the majority of RNA polymerase II (RNAPII) promoters in mouse embryonic stem cells (mESCs), and this activity correlates with CpG islands. Here we report the characterization of upstream antisense transcription in regions encoding transcription start site associated...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Flynn, Ryan A., Almada, Albert E., Zamudio, Jesse R., Sharp, Phillip A.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 2011
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3127934/
https://ncbi.nlm.nih.gov/pubmed/21670248
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1106630108
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