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Divergent transcription from active promoters

Initiation by RNA polymerase II (RNAPII) is thought to occur unidirectionally from most genes. We have identified a class of short RNAs in mammalian cells that challenges this convention, suggesting the existence of widespread divergent transcription. Transcription start site-associated RNAs (TSSa-R...

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Detalhes bibliográficos
Main Authors: Seila, Amy C., Calabrese, J. Mauro, Levine, Stuart S., Yeo, Gene W., Rahl, Peter B., Flynn, Ryan A., Young, Richard A., Sharp, Phillip A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2692996/
https://ncbi.nlm.nih.gov/pubmed/19056940
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1162253
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