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RNA sequence analysis defines Dicer's role in mouse embryonic stem cells

Short RNA expression was analyzed from Dicer-positive and Dicer-knockout mouse embroyonic stem (ES) cells, using high-throughput pyrosequencing. A correlation of miRNA quantification with sequencing frequency estimates that there are 110,000 miRNAs per ES cell, the majority of which can be accounted...

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Autori principali: Calabrese, J. Mauro, Seila, Amy C., Yeo, Gene W., Sharp, Phillip A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2007
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2084302/
https://ncbi.nlm.nih.gov/pubmed/17989215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0709193104
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