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Antisense RNA polymerase II divergent transcripts are P-TEFb dependent and substrates for the RNA exosome

Divergent transcription occurs at the majority of RNA polymerase II (RNAPII) promoters in mouse embryonic stem cells (mESCs), and this activity correlates with CpG islands. Here we report the characterization of upstream antisense transcription in regions encoding transcription start site associated...

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Detalhes bibliográficos
Main Authors: Flynn, Ryan A., Almada, Albert E., Zamudio, Jesse R., Sharp, Phillip A.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3127934/
https://ncbi.nlm.nih.gov/pubmed/21670248
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1106630108
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