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A homeotic mutation in the trithorax SET domain impedes histone binding

Trithorax (TRX) is a Drosophila SET domain protein that is required for the correct expression of homeotic genes. Here, we show that the TRX SET domain efficiently binds to core histones and nucleosomes. The primary target for the SET domain is histone H3 and binding requires the N-terminal histone...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Katsani, Katerina R., Arredondo, Juan J., Kal, Arnoud J., Verrijzer, C. Peter
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Cold Spring Harbor Laboratory Press 2001
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC312775/
https://ncbi.nlm.nih.gov/pubmed/11544176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.201901
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