A homeotic mutation in the trithorax SET domain impedes histone binding
Trithorax (TRX) is a Drosophila SET domain protein that is required for the correct expression of homeotic genes. Here, we show that the TRX SET domain efficiently binds to core histones and nucleosomes. The primary target for the SET domain is histone H3 and binding requires the N-terminal histone...
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| Pubblicato in: | Genes Dev |
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| Autori principali: | , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Cold Spring Harbor Laboratory Press
2001
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC312775/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11544176/ https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.201901 |
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