A homeotic mutation in the trithorax SET domain impedes histone binding
Trithorax (TRX) is a Drosophila SET domain protein that is required for the correct expression of homeotic genes. Here, we show that the TRX SET domain efficiently binds to core histones and nucleosomes. The primary target for the SET domain is histone H3 and binding requires the N-terminal histone...
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| Gepubliceerd in: | Genes Dev |
|---|---|
| Hoofdauteurs: | , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Cold Spring Harbor Laboratory Press
2001
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC312775/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11544176/ https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.201901 |
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