Human SMG-1, a novel phosphatidylinositol 3-kinase-related protein kinase, associates with components of the mRNA surveillance complex and is involved in the regulation of nonsense-mediated mRNA decay

Nonsense-mediated mRNA decay (NMD) is a conserved surveillance mechanism that eliminates imperfect mRNAs that contain premature translation termination codons (PTCs) and code for nonfunctional or potentially harmful polypeptides. We show that a novel phosphatidylinositol 3-kinase-related protein kin...

Descrizione completa

Dettagli Bibliografici

Pubblicato in:	Genes Dev
Autori principali:	Yamashita, Akio, Ohnishi, Tetsuo, Kashima, Isao, Taya, Yoichi, Ohno, Shigeo
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Cold Spring Harbor Laboratory Press 2001
Soggetti:	Research Paper
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC312771/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11544179/ https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.913001
Tags:	Aggiungi Tag Nessun Tag, puoi essere il primo ad aggiungerne!!