SMG-5, required for C.elegans nonsense-mediated mRNA decay, associates with SMG-2 and protein phosphatase 2A

mRNAs that contain premature stop codons are degraded selectively and rapidly in eukaryotes, a phenomenon termed ‘nonsense-mediated mRNA decay’ (NMD). We report here molecular analysis of smg-5, which encodes a novel protein required for NMD in Caenorhabditis elegans. Using a combination of immunopr...

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Detalhes bibliográficos

Publicado no:	EMBO J
Principais autores:	Anders, Kirk R., Grimson, Andrew, Anderson, Philip
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Nature Publishing Group 2003
Assuntos:	Articles
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC140740/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12554664/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/cdg056
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