Identification and Characterization of Human Orthologues to Saccharomyces cerevisiae Upf2 Protein and Upf3 Protein (Caenorhabditis elegans SMG-4)

Nonsense-mediated mRNA decay (NMD), also called mRNA surveillance, is an important pathway used by all organisms that have been tested to degrade mRNAs that prematurely terminate translation and, as a consequence, eliminate the production of aberrant proteins that could be potentially harmful. In ma...

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Autores principales: Serin, Guillaume, Gersappe, Anand, Black, Jennifer D., Aronoff, Rachel, Maquat, Lynne E.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2001
Materias:
Gene Expression
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC88795/
https://ncbi.nlm.nih.gov/pubmed/11113196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.1.209-223.2001
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