SMG-5, required for C.elegans nonsense-mediated mRNA decay, associates with SMG-2 and protein phosphatase 2A
mRNAs that contain premature stop codons are degraded selectively and rapidly in eukaryotes, a phenomenon termed ‘nonsense-mediated mRNA decay’ (NMD). We report here molecular analysis of smg-5, which encodes a novel protein required for NMD in Caenorhabditis elegans. Using a combination of immunopr...
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| Vydáno v: | EMBO J |
|---|---|
| Hlavní autoři: | , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Nature Publishing Group
2003
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC140740/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12554664/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/cdg056 |
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