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SMG-5, required for C.elegans nonsense-mediated mRNA decay, associates with SMG-2 and protein phosphatase 2A
mRNAs that contain premature stop codons are degraded selectively and rapidly in eukaryotes, a phenomenon termed ‘nonsense-mediated mRNA decay’ (NMD). We report here molecular analysis of smg-5, which encodes a novel protein required for NMD in Caenorhabditis elegans. Using a combination of immunopr...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Oxford University Press
2003
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC140740/ https://ncbi.nlm.nih.gov/pubmed/12554664 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdg056 |
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