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Selective induction of E2F1 in response to DNA damage, mediated by ATM-dependent phosphorylation

Previous work has established a role for p53 in triggering apoptosis in response to DNA damage; p53 also induces apoptosis in response to deregulation of the Rb cell cycle pathway. The latter event is consistent with a role for the Rb-regulated E2F1 protein as a specific inducer of apoptosis and p53...

Täydet tiedot

Tallennettuna:
Julkaisussa:Genes Dev
Päätekijät: Lin, Weei-Chin, Lin, Fang-Tsyr, Nevins, Joseph R.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Cold Spring Harbor Laboratory Press 2001
Aiheet:
Research Paper
Linkit:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC312742/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11459832/
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