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Pds1 phosphorylation in response to DNA damage is essential for its DNA damage checkpoint function
In Saccharomyces cerevisiae, Pds1 is an anaphase inhibitor and plays an essential role in DNA damage and spindle checkpoint pathways. Pds1 is phosphorylated in response to DNA damage but not spindle disruption, indicating distinct mechanisms delaying anaphase entry. Phosphorylation of Pds1 is Mec1 a...
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| Главные авторы: | , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Cold Spring Harbor Laboratory Press
2001
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC312708/ https://ncbi.nlm.nih.gov/pubmed/11390356 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.893201 |
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