Pds1 phosphorylation in response to DNA damage is essential for its DNA damage checkpoint function

In Saccharomyces cerevisiae, Pds1 is an anaphase inhibitor and plays an essential role in DNA damage and spindle checkpoint pathways. Pds1 is phosphorylated in response to DNA damage but not spindle disruption, indicating distinct mechanisms delaying anaphase entry. Phosphorylation of Pds1 is Mec1 a...

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Veröffentlicht in:	Genes Dev
Hauptverfasser:	Wang, Hong, Liu, Dou, Wang, Yanchang, Qin, Jun, Elledge, Stephen J.
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Cold Spring Harbor Laboratory Press 2001
Schlagworte:	Research Paper
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC312708/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11390356/ https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.893201
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