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A mutation in the Gsk3–binding domain of zebrafish Masterblind/Axin1 leads to a fate transformation of telencephalon and eyes to diencephalon

Zebrafish embryos homozygous for the masterblind (mbl) mutation exhibit a striking phenotype in which the eyes and telencephalon are reduced or absent and diencephalic fates expand to the front of the brain. Here we show that mbl(−/−) embryos carry an amino-acid change at a conserved site in the Wnt...

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Detalhes bibliográficos
Main Authors: Heisenberg, Carl-Philipp, Houart, Corinne, Take-uchi, Masaya, Rauch, Gerd-Jörg, Young, Neville, Coutinho, Pedro, Masai, Ichiro, Caneparo, Luca, Concha, Miguel L., Geisler, Robert, Dale, Trevor C., Wilson, Stephen W., Stemple, Derek L.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2001
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC312705/
https://ncbi.nlm.nih.gov/pubmed/11390362
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.194301
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