Interaction among Gsk-3, Gbp, Axin, and APC in Xenopus Axis Specification

Glycogen synthase kinase 3 (GSK-3) is a constitutively active kinase that negatively regulates its substrates, one of which is β-catenin, a downstream effector of the Wnt signaling pathway that is required for dorsal–ventral axis specification in the Xenopus embryo. GSK-3 activity is regulated throu...

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Detalhes bibliográficos
Main Authors: Farr, Gist H., Ferkey, Denise M., Yost, Cynthia, Pierce, Sarah B., Weaver, Carole, Kimelman, David
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2000
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2169372/
https://ncbi.nlm.nih.gov/pubmed/10684251
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