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MKK7 is an essential component of the JNK signal transduction pathway activated by proinflammatory cytokines

Mitogen-activated protein kinases (MAPK) are activated by phosphorylation on Thr and Tyr by MAPK kinases. Two MAPK kinases (MKK4 and MKK7) can activate the c-Jun NH(2)-terminal kinase (JNK) group of MAPK in vitro. JNK is phosphorylated preferentially on Tyr by MKK4 and on Thr by MKK7. Targeted gene-...

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Detalhes bibliográficos
Main Authors: Tournier, Cathy, Dong, Chen, Turner, Tod K., Jones, Stephen N., Flavell, Richard A., Davis, Roger J.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC312702/
https://ncbi.nlm.nih.gov/pubmed/11390361
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.888501
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