MKK7 is an essential component of the JNK signal transduction pathway activated by proinflammatory cytokines
Mitogen-activated protein kinases (MAPK) are activated by phosphorylation on Thr and Tyr by MAPK kinases. Two MAPK kinases (MKK4 and MKK7) can activate the c-Jun NH(2)-terminal kinase (JNK) group of MAPK in vitro. JNK is phosphorylated preferentially on Tyr by MKK4 and on Thr by MKK7. Targeted gene-...
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| Vydáno v: | Genes Dev |
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| Hlavní autoři: | , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Cold Spring Harbor Laboratory Press
2001
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC312702/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11390361/ https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.888501 |
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