MKK7 is an essential component of the JNK signal transduction pathway activated by proinflammatory cytokines

Mitogen-activated protein kinases (MAPK) are activated by phosphorylation on Thr and Tyr by MAPK kinases. Two MAPK kinases (MKK4 and MKK7) can activate the c-Jun NH(2)-terminal kinase (JNK) group of MAPK in vitro. JNK is phosphorylated preferentially on Tyr by MKK4 and on Thr by MKK7. Targeted gene-...

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Pubblicato in:	Genes Dev
Autori principali:	Tournier, Cathy, Dong, Chen, Turner, Tod K., Jones, Stephen N., Flavell, Richard A., Davis, Roger J.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Cold Spring Harbor Laboratory Press 2001
Soggetti:	Research Paper
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC312702/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11390361/ https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.888501
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