The Virulence of 1997 H5N1 Influenza Viruses in the Mouse Model Is Increased by Correcting a Defect in Their NS1 Proteins

The NS1 protein of human influenza A viruses binds the 30-kDa subunit of the cleavage and polyadenylation specificity factor (CPSF30), a protein required for 3′ end processing of cellular pre-mRNAs, thereby inhibiting production of beta interferon (IFN-β) mRNA. The NS1 proteins of pathogenic 1997 H5...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Spesock, April, Malur, Meghana, Hossain, M. Jaber, Chen, Li-Mei, Njaa, Bradley L., Davis, Charles T., Lipatov, Aleksandr S., York, Ian A., Krug, Robert M., Donis, Ruben O.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2011
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3126612/
https://ncbi.nlm.nih.gov/pubmed/21593152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00417-11
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados