The NS1 Gene Contributes to the Virulence of H5N1 Avian Influenza Viruses

In the present study, we explored the genetic basis underlying the virulence and host range of two H5N1 influenza viruses in chickens. A/goose/Guangdong/1/96 (GS/GD/1/96) is a highly pathogenic virus for chickens, whereas A/goose/Guangdong/2/96 (GS/GD/2/96) is unable to replicate in chickens. These...

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Detalhes bibliográficos
Main Authors: Li, Zejun, Jiang, Yongping, Jiao, Peirong, Wang, Aiqin, Zhao, Fengju, Tian, Guobin, Wang, Xijun, Yu, Kangzhen, Bu, Zhigao, Chen, Hualan
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2006
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1642184/
https://ncbi.nlm.nih.gov/pubmed/16971424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00993-06
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