Molecular Basis for Mycophenolic Acid Biosynthesis in Penicillium brevicompactum

Mycophenolic acid (MPA) is the active ingredient in the increasingly important immunosuppressive pharmaceuticals CellCept (Roche) and Myfortic (Novartis). Despite the long history of MPA, the molecular basis for its biosynthesis has remained enigmatic. Here we report the discovery of a polyketide sy...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Regueira, Torsten Bak, Kildegaard, Kanchana Rueksomtawin, Hansen, Bjarne Gram, Mortensen, Uffe H., Hertweck, Christian, Nielsen, Jens
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2011
Fag:
Biotechnology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3126426/
https://ncbi.nlm.nih.gov/pubmed/21398490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.03015-10
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker