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Molecular Basis for Mycophenolic Acid Biosynthesis in Penicillium brevicompactum
Mycophenolic acid (MPA) is the active ingredient in the increasingly important immunosuppressive pharmaceuticals CellCept (Roche) and Myfortic (Novartis). Despite the long history of MPA, the molecular basis for its biosynthesis has remained enigmatic. Here we report the discovery of a polyketide sy...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3126426/ https://ncbi.nlm.nih.gov/pubmed/21398490 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.03015-10 |
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