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DEVELOPMENT OF A NOVEL ASSAY FOR HUMAN TYROSYL DNA PHOSPHODIESTERASE 2
Tyrosyl DNA phosphodiesterase 2 (TDP2), a newly discovered enzyme that cleaves 5′-phosphotyrosyl bonds, is a potential target for chemotherapy. TDP2 possesses both 3′- and 5′-tyrosyl-DNA phosphodiesterase activity, which is generally measured in a gel-based assay using 3′- and 5′-phosphotyrosyl link...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3125436/ https://ncbi.nlm.nih.gov/pubmed/21620793 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ab.2011.05.008 |
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