Retrospective exploratory analysis of VEGF polymorphisms in the prediction of benefit from first-line FOLFIRI plus bevacizumab in metastatic colorectal cancer

BACKGROUND: Molecular predictors of bevacizumab efficacy in colorectal cancer have not been identified yet. Specific VEGF polymorphisms may affect gene transcription and therefore indirectly influence the efficacy of bevacizumab. METHODS: Genomic DNA of 111 consecutive metastatic colorectal cancer p...

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Detalhes bibliográficos
Main Authors: Loupakis, Fotios, Ruzzo, Annamaria, Salvatore, Lisa, Cremolini, Chiara, Masi, Gianluca, Frumento, Paolo, Schirripa, Marta, Catalano, Vincenzo, Galluccio, Nadia, Canestrari, Emanuele, Vincenzi, Bruno, Santini, Daniele, Bencardino, Katia, Ricci, Vincenzo, Manzoni, Mariangela, Danova, Marco, Tonini, Giuseppe, Magnani, Mauro, Falcone, Alfredo, Graziano, Francesco
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3125285/
https://ncbi.nlm.nih.gov/pubmed/21669012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-11-247
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