Genetic modulation of the interleukin 6 (IL-6) system in patients with advanced gastric cancer: a background for an alternative target therapy

ABSTRACTS: BACKGROUND: IL-6 triggers oncogenic/angiogenic signals and the cytokine-dependent pro-cachexia cascade. The prognostic role of the functional IL-6 (promoter) rs1800795 and the IL-6R (receptor) rs8192284 single nucleotide polymorphisms (SNP) was studied in patients with advanced gastric ca...

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Detalhes bibliográficos
Main Authors: Ruzzo, Annamaria, Catalano, Vincenzo, Canestrari, Emanuele, Giacomini, Elisa, Santini, Daniele, Tonini, Giuseppe, Vincenzi, Bruno, Fiorentini, Giammaria, Magnani, Mauro, Graziano, Francesco
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4046495/
https://ncbi.nlm.nih.gov/pubmed/24886605
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-14-357
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