Liver-only metastatic colorectal cancer patients and thymidylate synthase polymorphisms for predicting response to 5-fluorouracil-based chemotherapy

We investigated the association between thymidylate synthase (TS) germline polymorphisms and response to 5-fluorouracil-based chemotherapy in 80 patients with liver-only metastatic colorectal cancer (MCRC). The tandem repeat polymorphism (VNTR) in TS 5′-untranslated region (5′-UTR), which consists o...

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Hlavní autoři: Graziano, F, Ruzzo, A, Loupakis, F, Santini, D, Catalano, V, Canestrari, E, Maltese, P, Bisonni, R, Fornaro, L, Baldi, G, Masi, G, Falcone, A, Tonini, G, Giordani, P, Alessandroni, P, Giustini, L, Vincenzi, B, Magnani, M
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2008
Témata:
Clinical Study
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2528158/
https://ncbi.nlm.nih.gov/pubmed/18728661
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6604555
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