Thiazolides as Novel Antiviral Agents: I. Inhibition of Hepatitis B Virus Replication

We report the syntheses and activities of a wide range of thiazolides [viz. 2-hydroxyaroyl-N-(thiazol-2-yl)amides] against hepatitis B virus replication, with QSAR analysis of our results. The prototypical thiazolide, nitazoxanide [2-hydroxybenzoyl-N-(5-nitrothiazol-2-yl)amide; NTZ] 1 is a broad spe...

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Bibliografiset tiedot
Päätekijät: Stachulski, Andrew V., Pidathala, Chandrakala, Row, Eleanor C., Sharma, Raman, Berry, Neil G., Iqbal, Mazhar, Bentley, Joanne, Allman, Sarah A., Edwards, Geoffrey, Helm, Alison, Hellier, Jennifer, Korba, Brent E., Semple, J. Edward, Rossignol, Jean-Francois
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2011
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3124649/
https://ncbi.nlm.nih.gov/pubmed/21553812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm200153p
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