In Vitro Efficacies of Nitazoxanide and Other Thiazolides against Neospora caninum Tachyzoites Reveal Antiparasitic Activity Independent of the Nitro Group

The thiazolide nitazoxanide [2-acetolyloxy-N-(5-nitro-2-thiazolyl)benzamide] (NTZ) exhibits a broad spectrum of activities against a wide variety of intestinal and tissue-dwelling helminths, protozoa, and enteric bacteria infecting animals and humans. The drug has been postulated to act via reductio...

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Detalhes bibliográficos
Main Authors: Esposito, Marco, Stettler, Rebecca, Moores, Shelley L., Pidathala, Chandrakala, Müller, Norbert, Stachulski, Andrew, Berry, Neil G., Rossignol, Jean-Francois, Hemphill, Andrew
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Mechanisms of Action: Physiological Effects
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1195425/
https://ncbi.nlm.nih.gov/pubmed/16127045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.49.9.3715-3723.2005
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