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Conditional deletion of SLP-76 in mature T cells abrogates peripheral immune responses(1)

The adaptor protein Src homology 2 domain-containing leukocyte-specific protein of 76 kDa (SLP-76) is central to the organization of intracellular signaling downstream of the T cell receptor (TCR). Evaluation of its role in mature, primary T cells has been hampered by developmental defects that occu...

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Detalhes bibliográficos
Main Authors: Wu, Gregory F., Corbo, Evann, Schmidt, Michelle, Smith-Garvin, Jennifer E., Riese, Matthew J., Jordan, Martha S., Laufer, Terri M., Brown, Eric J., Maltzman, Jonathan S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3124603/
https://ncbi.nlm.nih.gov/pubmed/21469089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201040809
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