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Metabolism of bupropion by baboon hepatic and placental microsomes

The aim of this investigation was to determine the biotransformation of bupropion by baboon hepatic and placental microsomes, identify the enzyme(s) catalyzing the reaction(s) and determine its kinetics. Bupropion was metabolized by baboon hepatic and placental microsomes to hydroxybupropion (OH-BUP...

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Detalhes bibliográficos
Main Authors: Wang, Xiaoming, Abdelrahman, Doaa R., Fokina, Valentina M., Hankins, Gary D.V., Ahmed, Mahmoud S., Nanovskaya, Tatiana N.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3124571/
https://ncbi.nlm.nih.gov/pubmed/21570381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2011.04.014
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