Metabolism of bupropion by baboon hepatic and placental microsomes

The aim of this investigation was to determine the biotransformation of bupropion by baboon hepatic and placental microsomes, identify the enzyme(s) catalyzing the reaction(s) and determine its kinetics. Bupropion was metabolized by baboon hepatic and placental microsomes to hydroxybupropion (OH-BUP...

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Bibliografiske detaljer
Main Authors: Wang, Xiaoming, Abdelrahman, Doaa R., Fokina, Valentina M., Hankins, Gary D.V., Ahmed, Mahmoud S., Nanovskaya, Tatiana N.
Format: Artigo
Sprog:Inglês
Udgivet: 2011
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3124571/
https://ncbi.nlm.nih.gov/pubmed/21570381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2011.04.014
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