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Metabolism of bupropion by baboon hepatic and placental microsomes
The aim of this investigation was to determine the biotransformation of bupropion by baboon hepatic and placental microsomes, identify the enzyme(s) catalyzing the reaction(s) and determine its kinetics. Bupropion was metabolized by baboon hepatic and placental microsomes to hydroxybupropion (OH-BUP...
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| Autores principales: | , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2011
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3124571/ https://ncbi.nlm.nih.gov/pubmed/21570381 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2011.04.014 |
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