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Metabolism of bupropion by baboon hepatic and placental microsomes

The aim of this investigation was to determine the biotransformation of bupropion by baboon hepatic and placental microsomes, identify the enzyme(s) catalyzing the reaction(s) and determine its kinetics. Bupropion was metabolized by baboon hepatic and placental microsomes to hydroxybupropion (OH-BUP...

詳細記述

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書誌詳細
主要な著者: Wang, Xiaoming, Abdelrahman, Doaa R., Fokina, Valentina M., Hankins, Gary D.V., Ahmed, Mahmoud S., Nanovskaya, Tatiana N.
フォーマット: Artigo
言語:Inglês
出版事項: 2011
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3124571/
https://ncbi.nlm.nih.gov/pubmed/21570381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2011.04.014
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