Functional Stability of Unliganded Envelope Glycoprotein Spikes among Isolates of Human Immunodeficiency Virus Type 1 (HIV-1)

The HIV-1 envelope glycoprotein (Env) spike is challenging to study at the molecular level, due in part to its genetic variability, structural heterogeneity and lability. However, the extent of lability in Env function, particularly for primary isolates across clades, has not been explored. Here, we...

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Main Authors: Agrawal, Nitish, Leaman, Daniel P., Rowcliffe, Eric, Kinkead, Heather, Nohria, Raman, Akagi, Junya, Bauer, Katherine, Du, Sean X., Whalen, Robert G., Burton, Dennis R., Zwick, Michael B.
格式: Artigo
語言:Inglês
出版: Public Library of Science 2011
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3124497/
https://ncbi.nlm.nih.gov/pubmed/21738637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0021339
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