Functional Stability of Unliganded Envelope Glycoprotein Spikes among Isolates of Human Immunodeficiency Virus Type 1 (HIV-1)

The HIV-1 envelope glycoprotein (Env) spike is challenging to study at the molecular level, due in part to its genetic variability, structural heterogeneity and lability. However, the extent of lability in Env function, particularly for primary isolates across clades, has not been explored. Here, we...

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Detalhes bibliográficos
Main Authors: Agrawal, Nitish, Leaman, Daniel P., Rowcliffe, Eric, Kinkead, Heather, Nohria, Raman, Akagi, Junya, Bauer, Katherine, Du, Sean X., Whalen, Robert G., Burton, Dennis R., Zwick, Michael B.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3124497/
https://ncbi.nlm.nih.gov/pubmed/21738637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0021339
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