Functional Stability of Unliganded Envelope Glycoprotein Spikes among Isolates of Human Immunodeficiency Virus Type 1 (HIV-1)

The HIV-1 envelope glycoprotein (Env) spike is challenging to study at the molecular level, due in part to its genetic variability, structural heterogeneity and lability. However, the extent of lability in Env function, particularly for primary isolates across clades, has not been explored. Here, we...

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Bibliografiske detaljer
Main Authors:	Agrawal, Nitish, Leaman, Daniel P., Rowcliffe, Eric, Kinkead, Heather, Nohria, Raman, Akagi, Junya, Bauer, Katherine, Du, Sean X., Whalen, Robert G., Burton, Dennis R., Zwick, Michael B.
Format:	Artigo
Sprog:	Inglês
Udgivet:	Public Library of Science 2011
Fag:	Research Article
Online adgang:	https://ncbi.nlm.nih.gov/pmc/articles/PMC3124497/ https://ncbi.nlm.nih.gov/pubmed/21738637 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0021339
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Functional Stability of Unliganded Envelope Glycoprotein Spikes among Isolates of Human Immunodeficiency Virus Type 1 (HIV-1)

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