Inactivation of Bmp4 from the Tbx1 Expression Domain Causes Abnormal Pharyngeal Arch Artery and Cardiac Outflow Tract Remodeling

Eitemau Tebyg

• Mesodermal expression of Tbx1 is necessary and sufficient for pharyngeal arch and cardiac outflow tract development
  gan: Zhang, Zhen, et al.
  Cyhoeddwyd: (2006)
• Fgf8 expression in the Tbx1 domain causes skeletal abnormalities and modifies the aortic arch but not the outflow tract phenotype of Tbx1 mutants
  gan: Vitelli, Francesca, et al.
  Cyhoeddwyd: (2006)
• Bmp4 signaling is required for outflow-tract septation and branchial-arch artery remodeling
  gan: Liu, Wei, et al.
  Cyhoeddwyd: (2004)
• Dicer activity in neural crest cells is essential for craniofacial organogenesis and pharyngeal arch artery morphogenesis
  gan: Nie, Xuguang, et al.
  Cyhoeddwyd: (2011)
• Disruption of Smad4 in neural crest cells leads to mid-gestation death with pharyngeal arch, craniofacial and cardiac defects
  gan: Nie, Xuguang, et al.
  Cyhoeddwyd: (2008)