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Inactivation of Bmp4 from the Tbx1 Expression Domain Causes Abnormal Pharyngeal Arch Artery and Cardiac Outflow Tract Remodeling

Maldevelopment of outflow tract and aortic arch arteries is among the most common forms of human congenital heart diseases. Both Bmp4 and Tbx1 are known to play critical roles during cardiovascular development. Expression of these two genes partially overlaps in pharyngeal arch areas in mouse embryo...

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Autori principali: Nie, Xuguang, Brown, Christopher B., Wang, Qin, Jiao, Kai
Natura: Artigo
Lingua:Inglês
Pubblicazione: S. Karger AG 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3124451/
https://ncbi.nlm.nih.gov/pubmed/21123999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000321170
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