Chromosome-wide mapping of DNA methylation patterns in normal and malignant prostate cells reveals pervasive methylation of gene-associated and conserved intergenic sequences

BACKGROUND: DNA methylation has been linked to genome regulation and dysregulation in health and disease respectively, and methods for characterizing genomic DNA methylation patterns are rapidly emerging. We have developed/refined methods for enrichment of methylated genomic fragments using the meth...

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Detalhes bibliográficos
Main Authors: Yegnasubramanian, Srinivasan, Wu, Zhijin, Haffner, Michael C, Esopi, David, Aryee, Martin J, Badrinath, Raghav, He, Tony L, Morgan, James D, Carvalho, Benilton, Zheng, Qizhi, De Marzo, Angelo M, Irizarry, Rafael A, Nelson, William G
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3124442/
https://ncbi.nlm.nih.gov/pubmed/21669002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-12-313
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